Prostate Cancer Growth
Origins in Glandular Cells
Although several other cell types are found in the prostate, over 99% of prostate cancers develop from glandular cells. Glandular cells produce the seminal fluid that is secreted by the prostate. The medical term for a cancer that starts in glandular cells is adenocarcinoma. Because other types of prostate cancer are so rare, if you have prostate cancer, it is almost certain to be adenocarcinoma.
Most prostate cancers grow very slowly. Autopsy studies show that many older men who died of other diseases also had prostate cancer that neither they nor their doctors were aware of. Some prostate cancers, however, can grow and spread quickly. Even with the latest methods, it is difficult to tell which cancers may become life threatening and which likely do not require treatment.
Changes in Prostate Gland Cells - PIN
Some doctors believe that prostate cancer begins with a condition called prostatic intraepithelial neoplasia (PIN). PIN begins to appear in men in their 20s. Almost 50% of men have PIN by the time they reach 50. In this condition there are changes in the microscopic appearance (size, shape, etc.) of prostate gland cells. These changes are classified as either low-grade, meaning they appear almost normal, or high-grade, meaning they look abnormal. If you have been diagnosed with a high grade PIN on a prostate biopsy, there is a 30% to 50% chance that cancer is also present within your prostate. For this reason, men diagnosed with high-grade PIN are watched carefully and have periodic prostate biopsies.1
da Vinci Treatment Options for Prostate Cancer
- Prostate Cancer. National Institutes of Health Available from: http://www.cancer.gov/cancertopics/pdq/treatment/prostate/patient
All surgery presents risk, including da Vinci Surgery. Results, including cosmetic results, may vary. Serious complications may occur in any surgery, up to and including death. Examples of serious and life-threatening complications, which may require hospitalization, include injury to tissues or organs; bleeding; infection, and internal scarring that can cause long-lasting dysfunction or pain. Temporary pain or nerve injury has been linked to the inverted position often used during abdominal and pelvic surgery. Patients should understand that risks of surgery include potential for human error and potential for equipment failure. Risk specific to minimally invasive surgery may include: a longer operative time; the need to convert the procedure to an open approach; or the need for additional or larger incision sites. Converting the procedure to open could mean a longer operative time, long time under anesthesia, and could lead to increased complications. Research suggests that there may be an increased risk of incision-site hernia with single-incision surgery. Patients who bleed easily, have abnormal blood clotting, are pregnant or morbidly obese are typically not candidates for minimally invasive surgery, including da Vinci Surgery. Other surgical approaches are available. Patients should review the risks associated with all surgical approaches. They should talk to their doctors about their surgical experience and to decide if da Vinci is right for them. For more complete information on surgical risks, safety and indications for use, please refer to http://www.davincisurgery.com/da-vinci-surgery/safety-information.php.
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PN 1002332 Rev A 04/2013 U 07/06/2012